Article
Genome-Wide Association and Trans-ethnic Meta-Analysis for Advanced Diabetic Kidney Disease: Family Investigation of Nephropathy and Diabetes (FIND).
PLoS genetics - 1 Aug 2015
Iyengar Sudha K, Sedor John R, Freedman Barry I, Kao W H Linda, Kretzler Matthias, Keller Benjamin J, Abboud Hanna E, Adler Sharon G, Best Lyle G, Bowden Donald W, Burlock Allison, Chen Yii-Der Ida, Cole Shelley A, Comeau Mary E, Curtis Jeffrey M, Divers Jasmin, Drechsler Christiane, Duggirala Ravi, Elston Robert C, Guo Xiuqing, Huang Huateng, Hoffmann Michael Marcus, Howard Barbara V, Ipp Eli, Kimmel Paul L, Klag Michael J, Knowler William C, Kohn Orly F, Leak Tennille S, Leehey David J, Li Man, Malhotra Alka, März Winfried, Nair Viji, Nelson Robert G, Nicholas Susanne B, O'Brien Stephen J, Pahl Madeleine V, Parekh Rulan S, Pezzolesi Marcus G, Rasooly Rebekah S, Rotimi Charles N, Rotter Jerome I, Schelling Jeffrey R, Seldin Michael F, Shah Vallabh O, Smiles Adam M, Smith Michael W, Taylor Kent D, Thameem Farook, Thornley-Brown Denyse P, Truitt Barbara J, Wanner Christoph, Weil E Jennifer, Winkler Cheryl A, Zager Philip G, Igo Robert P, Hanson Robert L, Langefeld Carl D
Abstract excerpt
Diabetic kidney disease (DKD) is the most common etiology of chronic kidney disease (CKD) in the industrialized world and accounts for much of the excess mortality in patients with diabetes mellitus. Approximately 45% of U.S. patients with incident end-stage kidney disease (ESKD) have DKD. Independent of glycemic control, DKD aggregates in families and has higher incidence rates in African, Mexican, and American...
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