Article
Disruption of the GABA shunt affects mitochondrial respiration and virulence in the cereal pathogen Fusarium graminearum.
Molecular microbiology - 1 Dec 2015
Bönnighausen Jakob, Gebhard Daniel, Kröger Cathrin, Hadeler Birgit, Tumforde Thomas, Lieberei Reinhard, Bergemann Jörg, Schäfer Wilhelm, Bormann Jörg
Abstract excerpt
The cereal pathogen Fusarium graminearum threatens food and feed production worldwide. It reduces the yield and poisons the remaining kernels with mycotoxins, notably deoxynivalenol (DON). We analyzed the importance of gamma-aminobutanoic acid (GABA) metabolism for the life cycle of this fungal pathogen. GABA metabolism in F. graminearum is partially regulated by the global nitrogen regulator AreA. Genetic...
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