Article
Rosacea: The Blessing of the Celts - An Approach to Pathogenesis Through Translational Research.
Acta dermato-venereologica - 1 Feb 2016
Melnik Bodo C
Abstract excerpt
Increased expression of cathelicidin antimicrobial peptide (CAMP) is related to the pathogenesis of rosacea. CAMP plays a crucial role in antimicrobial defences, such as the killing of mycobacteria. CAMP gene expression is regulated by vitamin D-dependent (VDR) and vitamin D-independent (C/EBPα) transcription factors. VDR-dependent CAMP expression is sufficient during the summer months in Nordic countries, but...
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