Article
Repeated Screening Can Be Restricted to At-Genetic-Risk Birth Cohorts.
Journal of pediatric gastroenterology and nutrition - 1 Feb 2016
Björck Sara, Lynch Kristian, Brundin Charlotte, Agardh Daniel
Abstract excerpt
OBJECTIVES: Celiac disease (CD) is associated with tissue transglutaminase autoantibodies (tTGAs) in individuals carrying the human leukocyte antigen (HLA) risk haplotypes DQA1*05:01-DQB1*02:01 (DQ2) and/or DQA1*03:01-DQB1*03:02 (DQ8). The aim of the study was to identify CD in an HLA-genotyped birth cohort prospectively screened for CD. METHODS: In the initial screening, 13,860 HLA-DQ-genotyped children were...
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