Article
Early Prediction of Response to Tyrosine Kinase Inhibitors by Quantification of EGFR Mutations in Plasma of NSCLC Patients.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Oct 2015
Marchetti Antonio, Palma John F, Felicioni Lara, De Pas Tommaso M, Chiari Rita, Del Grammastro Maela, Filice Giampaolo, Ludovini Vienna, Brandes Alba A, Chella Antonio, Malorgio Francesco, Guglielmi Flavio, De Tursi Michele, Santoro Armando, Crinò Lucio, Buttitta Fiamma
Abstract excerpt
INTRODUCTION: The potential to accurately quantify epidermal growth factor receptor (EGFR) mutations in plasma from non-small-cell lung cancer patients would enable more rapid and more frequent analyses to assess disease status; however, the utility of such analyses for clinical purposes has only recently started to explore. METHODS: Plasma samples were obtained from 69 patients with EGFR-mutated tumors and 21...
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