Article
Subtyping of the Legionella pneumophila "Ulm" outbreak strain using the CRISPR-Cas system.
International journal of medical microbiology : IJMM - 1 Dec 2015
Lück Christian, Brzuszkiewicz Elzbieta, Rydzewski Kerstin, Koshkolda Tetyana, Sarnow Katharina, Essig Andreas, Heuner Klaus
Abstract excerpt
In 2009/2010 an outbreak of Legionnaires' disease with 64 cases including four fatalities took place in the city of Ulm/Neu-Ulm in Germany. L. pneumophila serogroup 1, mAb type Knoxville, sequence type (ST) 62 was identified as the epidemic strain. This strain was isolated from eight patients and from a cooling tower in the city of Ulm. Based on whole genome sequencing data from one patient strain, we identified...
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