Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hepcidin and Host Defense against Infectious Diseases

20 Aug 2015

Abstract excerpt

Hepcidin is the master regulator of iron homeostasis in vertebrates. The synthesis of hepcidin is induced by systemic iron levels and by inflammatory stimuli. While the role of hepcidin in iron regulation is well established, its contribution to host defense is emerging as complex and multifaceted. In this review, we summarize the literature on the role of hepcidin as a mediator of antimicrobial immunity....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hemoglobinopathies and Related Disorders
Share to Iron Metabolism and Disorders
Share to Trace Elements in Health

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 26291319
DOI: 10.1371/journal.ppat.1004998

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hepcidin and Host Defense against Infectious DiseasesPMID 26291319Read ↗

The regulation of hepcidin and its effects on systemic and cellular iron metabolism.Semantic proximity Read ↗

Hepcidin: The Gatekeeper of Iron in Malaria ResistanceSemantic proximity Read ↗

The struggle for iron - a metal at the host-pathogen interfaceSemantic proximity Read ↗

Molecular regulation of hepatic expression of iron regulatory hormone hepcidin.Semantic proximity Read ↗

Ferroptosis: A mixed blessing for infectious diseasesSemantic proximity Read ↗

[Regulation of body iron homeostasis by hepcidin].Semantic proximity Read ↗

The Multifaceted Functions of Lactoferrin in Antimicrobial Defense and InflammationSemantic proximity Read ↗

Crosstalk of ferroptosis and oxidative stress in infectious diseasesSemantic proximity Read ↗

Ferroptosis in immunostimulation and immunosuppressionSemantic proximity Read ↗

Iron Acquisition Strategies of Bacterial PathogensSemantic proximity Read ↗

Iron Metabolism at the Interface between Host and Pathogen: From Nutritional Immunity to Antibacterial DevelopmentSemantic proximity Read ↗

Iron Pathways and Iron Chelation Approaches in Viral, Microbial, and Fungal InfectionsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.