[TGC Repeats in Intron 2 of the TCF4 Gene have a Good Predictive Power Regarding to Fuchs Endothelial Corneal Dystrophy].

doi:10.1055/s-0035-1546138

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Article

[TGC Repeats in Intron 2 of the TCF4 Gene have a Good Predictive Power Regarding to Fuchs Endothelial Corneal Dystrophy].

Klinische Monatsblatter fur Augenheilkunde - 1 Feb 2016

Luther M, Grünauer-Kloevekorn C, Weidle E, Passarge E, Rupprecht A, Hoffmann K, Foja S

Abstract excerpt

BACKGROUND: Fuchs endothelial corneal dystrophy (FECD) is one of the most common indications for corneal transplants. FECD is associated with various genes, e.g., COL8A2 or SLC4A11. Among other things a TGC trinucleotide repeat expansion in intron 2 of the TCF4 gene has been characterised in FECD patients and the allele G of the polymorphism rs613872 in intron 3 of the same gene has been associated with this...

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Identifiers

PMID: 26280645
DOI: 10.1055/s-0035-1546138

Genes

TCF4
LOXHD1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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