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Article

Mutation in PCDH15 may modify the phenotypic expression of the 7511T>C mutation in MT-TS1 in a Chinese Han family with maternally inherited nonsyndromic hearing loss.

International journal of pediatric otorhinolaryngology - 1 Oct 2015

Chen Dong-ye, Zhu Wei-dong, Chai Yong-chuan, Chen Ying, Sun Lianhua, Yang Tao, Wu Hao

Abstract excerpt

OBJECTIVES: Mutations in MT-TS1 have been found to be associated with nonsyndromic sensorineural hearing loss (SNHL). PCDH15 codes for protocadherin-15, a member of the cadherin superfamily of calcium-dependent cell-cell adhesion molecules. In this study, we analyzed the correlation of both MT-TS1 and PCDH15 mutations in a Chinese Han family segregating maternally inherited nonsyndromic SNHL. METHODS: We...

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Identifiers

PMID: 26279247
DOI: 10.1016/j.ijporl.2015.07.008

Genes

PCDH15
UCN

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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