Article
The Prevalence of Sickle Cell Disease and Its Implication for Newborn Screening in Germany (Hamburg Metropolitan Area).
Pediatric blood & cancer - 1 Jan 2016
Grosse Regine, Lukacs Zoltan, Cobos Paulina Nieves, Oyen Florian, Ehmen Christa, Muntau Birgit, Timmann Christian, Noack Bernd
Abstract excerpt
Sickle cell disease is among hereditary diseases with evidence that early diagnoses and treatment improves the clinical outcome. So far sickle cell disease has not been included in the German newborn screening program despite immigration from countries with populations at risk. To determine the birth prevalence we tested 17,018 newborns. High pressure liquid chromatography and subsequent molecular-genetic testing...
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