Article
Binding Patterns of Rotavirus Genotypes P[4], P[6], and P[8] in China with Histo-Blood Group Antigens.
PloS one - 1 Jan 2015
Ma Xin, Li Dan-di, Sun Xiao-Man, Guo Yan-Qing, Xiang Jing-Yao, Wang Wei-Huan, Zhang Li-Xia, Gu Qing-Jiu, Duan Zhao-Jun
Abstract excerpt
Rotaviruses (RVs) are an important cause of severe gastroenteritis in children. It has been found that RV may recognize the histo-blood group antigens (HBGAs) as ligands or receptors and bind HBGAs in a type-dependent manner. In this study, we investigated the binding specificity of VP8* proteins from human rotaviruses (RV) that are prevalent in China including genotypes P[4], P[6], and P[8]. Through the saliva-...
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