Continuous wound infusion of local anesthetic and steroid after major abdominal surgery: study protocol for a randomized controlled trial.

doi:10.1186/s13063-015-0874-z

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Article

Continuous wound infusion of local anesthetic and steroid after major abdominal surgery: study protocol for a randomized controlled trial.

Trials - 14 Aug 2015

Bugada Dario, De Gregori Manuela, Compagnone Christian, Muscoli Carolina, Raimondi Ferdinando, Bettinelli Silvia, Avanzini Maria Antonietta, Cobianchi Lorenzo, Peloso Andrea, Baciarello Marco, Dagostino Concetta, Giancotti Luigino A, Ilari Sara, Lauro Filomena, Grimaldi Stefania, Tasciotti Ennio, Fini Massimo, Saccani Jotti Gloria M R, Meschi Tiziana, Fanelli Guido, Allegri Massimo

Abstract excerpt

BACKGROUND: Inflammatory response is one of the key components of pain perception. Continuous infusion (CWI) of local anesthetics has been shown to be effective in controlling pain and reducing postoperative morphine consumption, but the effect of adding a potent anti-inflammatory drug (such as a steroid) has never been addressed. In our study, we want to investigate the effect of CWI with local anesthetic +...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26272452
DOI: 10.1186/s13063-015-0874-z
PMCID: PMC4536778

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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