Article
Discussing the putative role of obesity-associated genes in the etiopathogenesis of eating disorders.
Pharmacogenomics - 1 Jan 2015
Gervasini Guillermo, Gamero-Villarroel Carmen
Abstract excerpt
In addition to the identification of mutations clearly related to Mendelian forms of obesity; genome-wide association studies and follow-up studies have in the last years pinpointed several loci associated with BMI. These genetic alterations are located in or near genes expressed in the hypothalamus that are involved in the regulation of eating behavior. Accordingly, it seems plausible that these SNPs, or others...
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