Article
[Applicability of MALDI Mass Spectrometry for Diagnostics of Phase Variants in Bacterial Populations].
Mikrobiologiia - 1 Jan 2000
Kryazhevskikh N A, Loiko N G, Demkina E V, Mulyukin A L, Lebedev A T, Gaponov A M, Tutel'yan A V, Nikolaeva Yu A, El'-Registan G I
Abstract excerpt
Efficiency of MALDI mass spectrometry for differentiation between phenotypic phase variants (in colony morphology and virulence/avirulence) was investigated.for saprotrophic and opportunistically pathogenic bacteria of five genera (Acinetobacter, Arthrobacter, Rhodococcus, Corynebacterium, and Escherichia). Analysis of MALDI spectra (on the SA and HCCA matrices) included: (1) determination of similarity of the...
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