[High frequency of ancestral allele of the TJP1 polymorphism rs2291166 in Mexican population, conformational effect and applications in surgery and medicine].

doi:10.1016/j.circir.2015.06.033

Article

[High frequency of ancestral allele of the TJP1 polymorphism rs2291166 in Mexican population, conformational effect and applications in surgery and medicine].

Cirugia y cirujanos - 1 Jan 2000

Ramirez-Garcia Sergio Alberto, Flores-Alvarado Luis Javier, Topete-González Luz Rosalba, Charles-Niño Claudia, Mazariegos-Rubi Manuel, Dávalos-Rodríguez Nory Omayra

Abstract excerpt

BACKGROUND: TJP1 gene encodes a ZO-1 protein that is required for the recruitment of occludins and claudins in tight junction, and is involved in cell polarisation. It has different variations, the frequency of which has been studied in different populations. In Mexico there are no studies of this gene. These are required because their polymorphisms can be used in studies associated with medicine and surgery....

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[High frequency of ancestral allele of the TJP1 polymorphism rs2291166 in Mexican population, conformational effect and applications in surgery and medicine].

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