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Deleterious BRCA1/2 mutations in an urban population of Black women.

Breast cancer research and treatment - 1 Aug 2015

Lynce Filipa, Smith Karen Lisa, Stein Julie, DeMarco Tiffani, Wang Yiru, Wang Hongkun, Fries Melissa, Peshkin Beth N, Isaacs Claudine

Abstract excerpt

Information on the prevalence of deleterious BRCA1 and BRCA2 (BRCA1/2) mutations in clinic-based populations of Black women is limited. In order to address this gap, we performed a retrospective study to determine the prevalence of deleterious BRCA1/2 mutations, predictors of having a mutation, and acceptance of risk-reducing surgeries in Black women. In an urban unselected clinic-based population, we evaluated...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 26250392
DOI: 10.1007/s10549-015-3527-8
PMCID: PMC5963698

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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