Article
A Genomic Approach to Unravel Host-Pathogen Interaction in Chelonians: The Example of Testudinid Herpesvirus 3.
PloS one - 1 Jan 2015
Origgi Francesco C, Tecilla Marco, Pilo Paola, Aloisio Fabio, Otten Patricia, Aguilar-Bultet Lisandra, Sattler Ursula, Roccabianca Paola, Romero Carlos H, Bloom David C, Jacobson Elliott R
Abstract excerpt
We report the first de novo sequence assembly and analysis of the genome of Testudinid herpesvirus 3 (TeHV3), one of the most pathogenic chelonian herpesviruses. The genome of TeHV3 is at least 150,080 nucleotides long, is arranged in a type D configuration and comprises at least 102 open reading frames extensively co-linear with those of Human herpesvirus 1. Consistently, the phylogenetic analysis positions...
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