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Production of recombinant VP1-derived virus-like particles from novel human polyomaviruses in yeast

3 Aug 2015

Abstract excerpt

BACKGROUND: Eleven new human polyomaviruses (HPyVs) have been identified in the last decade. Serological studies show that these novel HPyVs sub-clinically infect humans at an early age. The routes of infection, entry pathways, and cell tropism of new HPyVs remain unknown. VP1 proteins of polyomaviruses can assembly into virus-like particles (VLPs). As cell culturing systems for HPyV are currently not available,...

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PMID: 26239840
DOI: 10.1186/s12896-015-0187-z

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