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Article

Reduction of butyrate- and methane-producing microorganisms in patients with Irritable Bowel Syndrome.

Scientific reports - 4 Aug 2015

Pozuelo Marta, Panda Suchita, Santiago Alba, Mendez Sara, Accarino Anna, Santos Javier, Guarner Francisco, Azpiroz Fernando, Manichanh Chaysavanh

Abstract excerpt

The pathophysiology of irritable bowel syndrome (IBS) remains unclear. Here we investigated the microbiome of a large cohort of patients to identify specific signatures for IBS subtypes. We examined the microbiome of 113 patients with IBS and 66 healthy controls. A subset of these participants provided two samples one month apart. We analyzed a total of 273 fecal samples, generating more than 20 million 16S rRNA...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26239401
DOI: 10.1038/srep12693
PMCID: PMC4523847

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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