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Article

MAC: identifying and correcting annotation for multi-nucleotide variations.

BMC genomics - 1 Aug 2015

Wei Lei, Liu Lu T, Conroy Jacob R, Hu Qiang, Conroy Jeffrey M, Morrison Carl D, Johnson Candace S, Wang Jianmin, Liu Song

Abstract excerpt

BACKGROUND: Next-Generation Sequencing (NGS) technologies have rapidly advanced our understanding of human variation in cancer. To accurately translate the raw sequencing data into practical knowledge, annotation tools, algorithms and pipelines must be developed that keep pace with the rapidly evolving technology. Currently, a challenge exists in accurately annotating multi-nucleotide variants (MNVs). These...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26231518
DOI: 10.1186/s12864-015-1779-7
PMCID: PMC4521406

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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