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Article

Nonmuscle Myosin Heavy Chain IIA Mutation Predicts Severity and Progression of Sensorineural Hearing Loss in Patients With MYH9-Related Disease.

Ear and hearing - 1 Jan 2000

Verver Eva J J, Topsakal Vedat, Kunst Henricus P M, Huygen Patrick L M, Heller Paula G, Pujol-Moix Nuria, Savoia Anna, Benazzo Marco, Fierro Tiziana, Grolman Wilko, Gresele Paolo, Pecci Alessandro

Abstract excerpt

OBJECTIVES: MYH9-related disease (MYH9-RD) is an autosomal- dominant disorder deriving from mutations in MYH9, the gene for the nonmuscle myosin heavy chain (NMMHC)-IIA. MYH9-RD has a complex phenotype including congenital features, such as thrombocytopenia, and noncongenital manifestations, namely sensorineural hearing loss (SNHL), nephropathy, cataract, and liver abnormalities. The disease is caused by a...

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Source

Identifiers

PMID: 26226608
DOI: 10.1097/AUD.0000000000000198

Genes

MYH9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Nonmuscle Myosin Heavy Chain IIA Mutation Predicts Severity and Progression of Sensorineural Hearing Loss in Patients With MYH9-Related Disease.PMID 26226608Read ↗

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MYH9-Related Thrombocytopenia: Four Novel Variants Affecting the Tail Domain of the Non-Muscle Myosin Heavy Chain IIA Associated with a Mild Clinical Evolution of the Disorder.Semantic proximity Read ↗

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