Article
Abnormal septal convexity into the left ventricle occurs in subclinical hypertrophic cardiomyopathy.
Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance - 30 Jul 2015
Reant Patricia, Captur Gabriella, Mirabel Mariana, Nasis Arthur, M Sado Daniel, Maestrini Viviana, Castelletti Silvia, Manisty Charlotte, Herrey Anna S, Syrris Petros, Tome-Esteban Maite, Jenkins Sharon, Elliott Perry M, McKenna William J, Moon James C
Abstract excerpt
BACKGROUND: Sarcomeric gene mutations cause hypertrophic cardiomyopathy (HCM). In gene mutation carriers without left ventricular (LV) hypertrophy (G + LVH-), subclinical imaging biomarkers are recognized as predictors of overt HCM, consisting of anterior mitral valve leaflet elongation, myocardial crypts, hyperdynamic LV ejection fraction, and abnormal apical trabeculation. Reverse curvature of the...
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