Article
Design of an allele-specific PCR assay to genotype the rs12255372 SNP in a pilot study of association between common TCF7L2 polymorphisms and type 2 diabetes in Venezuelans.
Archives of endocrinology and metabolism - 21 Jul 2015
Moran Yeinmy, Labrador Luis, Camargo María Eugenia, Fernández David, Chiurillo Miguel Angel
Abstract excerpt
OBJECTIVE: The global burden of diabetes mellitus will impact strongly American countries in the coming decades. Type 2 diabetes mellitus (T2DM) is a multifactorial disease and the basis for its genetic susceptibility remains not fully understood. Different population studies have demonstrated that variants of the TCF7L2 gene are strongly associated with an increased risk of T2DM. Moreover, institutions or...
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