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Article

Total Lesion Glycolysis in Positron Emission Tomography Can Predict Gefitinib Outcomes in Non-Small-Cell Lung Cancer with Activating EGFR Mutation.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Aug 2015

Keam Bhumsuk, Lee Soo Jin, Kim Tae Min, Paeng Jin Chul, Lee Se-Hoon, Kim Dong-Wan, Jeon Yoon Kyung, Chung Doo Hyun, Kang Keon Wook, Chung June-Key, Heo Dae Seog

Abstract excerpt

INTRODUCTION: The purpose of this study was to evaluate the predictive role of quantitative metabolic parameters using total lesion glycolysis (TLG) in F-2-fluoro-2-deoxyglucose-positron emission tomography/computed tomography for developing gefitinib resistance in epidermal growth factor receptor (EGFR)-mutant non-small-cell lung cancer (NSCLC) patients treated with first-line gefitinib. METHODS: A total of 75...

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Identifiers

PMID: 26200273
DOI: 10.1097/JTO.0000000000000569

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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