Article
Epigenome data release: a participant-centered approach to privacy protection.
Genome biology - 17 Jul 2015
Dyke Stephanie O M, Cheung Warren A, Joly Yann, Ammerpohl Ole, Lutsik Pavlo, Rothstein Mark A, Caron Maxime, Busche Stephan, Bourque Guillaume, Rönnblom Lars, Flicek Paul, Beck Stephan, Hirst Martin, Stunnenberg Henk, Siebert Reiner, Walter Jörn, Pastinen Tomi
Abstract excerpt
Large-scale epigenome mapping by the NIH Roadmap Epigenomics Project, the ENCODE Consortium and the International Human Epigenome Consortium (IHEC) produces genome-wide DNA methylation data at one base-pair resolution. We examine how such data can be made open-access while balancing appropriate interpretation and genomic privacy. We propose guidelines for data release that both reduce ambiguity in the...
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