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Article

RUNX3 and CAMK2N1 hypermethylation as prognostic marker for epithelial ovarian cancer

15 Jul 2015

Abstract excerpt

Treatment of epithelial ovarian cancer consists of surgery plus platinum-taxane based chemotherapy. Neither prognostic nor predictive serum or tissue markers except BRCA1/2 mutations are available thus precluding individualized treatment. Aim of this study is the identification and validation of DNA-methylation markers with prognostic value. Genome-wide array analyses were used to determine methylation patterns...

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Share to Cancer-related molecular mechanisms research
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PMID: 26175272
DOI: 10.1002/ijc.29690

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