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Prognostic DNA Methylation Biomarkers in Ovarian Cancer

1 May 2006

Abstract excerpt

PURPOSE: Aberrant DNA methylation, now recognized as a contributing factor to neoplasia, often shows definitive gene/sequence preferences unique to specific cancer types. Correspondingly, distinct combinations of methylated loci can function as biomarkers for numerous clinical correlates of ovarian and other cancers. EXPERIMENTAL DESIGN: We used a microarray approach to identify methylated loci prognostic for...

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PMID: 16675572
DOI: 10.1158/1078-0432.ccr-05-1551

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