Article
Fragile X syndrome screening in Chinese children with unknown intellectual developmental disorder.
BMC pediatrics - 15 Jul 2015
Chen Xiaoli, Wang Jingmin, Xie Hua, Zhou Wenjuan, Wu Ye, Wang Jun, Qin Jian, Guo Jin, Gu Qiang, Zhang Xiaozhen, Ji Taoyun, Zhang Yu, Xiong Zhiming, Wang Liwen, Wu Xiru, Latham Gary J, Jiang Yuwu
Abstract excerpt
BACKGROUND: Fragile X syndrome is the most common genetic disorder of intellectual developmental disorder/mental retardation (IDD/MR). The prevalence of FXS in a Chinese IDD children seeking diagnosis/treatment in mainland China is unknown. METHODS: Patients with unknown moderate to severe IDD were recruited from two children's hospitals. Informed consent was obtained from the children's parents. The size of the...
Topics
- Adolescent
- Child
- Child, Preschool
- China
- Female
- Fragile X Mental Retardation Protein
- Fragile X Syndrome
- Genotype
- Humans
- Infant
- Intellectual Disability
- Male
- Pedigree
- Polymerase Chain Reaction