Article
Exogenous and endogenous determinants of vitamin K status in cystic fibrosis.
Scientific reports - 10 Jul 2015
Krzyżanowska Patrycja, Pogorzelski Andrzej, Skorupa Wojciech, Moczko Jerzy, Grebowiec Philip, Walkowiak Jarosław
Abstract excerpt
Cystic fibrosis (CF) patients are at high risk for vitamin K deficiency. The effects of vitamin K supplementation are very ambiguous. Therefore, we aimed to define the determinants of vitamin K deficiency in a large cohort of supplemented - 146 (86.9%) and non-supplemented - 22 (13.1%) CF patients. Vitamin K status was assessed using prothrombin inducted by vitamin K absence (PIVKA-II) and undercarboxylated...
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