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A Variegated Squirrel Bornavirus Associated with Fatal Human Encephalitis

8 Jul 2015

Abstract excerpt

Between 2011 and 2013, three breeders of variegated squirrels (Sciurus variegatoides) had encephalitis with similar clinical signs and died 2 to 4 months after onset of the clinical symptoms. With the use of a metagenomic approach that incorporated next-generation sequencing and real-time reverse-transcriptase quantitative polymerase chain reaction (RT-qPCR), the presence of a previously unknown bornavirus was...

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PMID: 26154788
DOI: 10.1056/nejmoa1415627

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