Article
CRF19_cpx is an Evolutionary fit HIV-1 Variant Strongly Associated With Rapid Progression to AIDS in Cuba.
EBioMedicine - 1 Mar 2015
Kouri Vivian, Khouri Ricardo, Alemán Yoan, Abrahantes Yeissel, Vercauteren Jurgen, Pineda-Peña Andrea-Clemencia, Theys Kristof, Megens Sarah, Moutschen Michel, Pfeifer Nico, Van Weyenbergh Johan, Pérez Ana B, Pérez Jorge, Pérez Lissette, Van Laethem Kristel, Vandamme Anne-Mieke
Abstract excerpt
BACKGROUND: Clinicians reported an increasing trend of rapid progression (RP) (AIDS within 3 years of infection) in Cuba. METHODS: Recently infected patients were prospectively sampled, 52 RP at AIDS diagnosis (AIDS-RP) and 21 without AIDS in the same time frame (non-AIDS). 22 patients were sampled at AIDS diagnosis (chronic-AIDS) retrospectively assessed as > 3 years infected. Clinical, demographic, virological,...
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