Article
A novel mice model of metabolic syndrome: the high-fat-high-fructose diet-fed ICR mice.
Experimental animals - 1 Jan 2015
Zhuhua Zhang, Zhiquan Wang, Zhen Yang, Yixin Niu, Weiwei Zhang, Xiaoyong Li, Yueming Liu, Hongmei Zhang, Li Qin, Qing Su
Abstract excerpt
Currently, the metabolic syndrome (MS) is occurring at growing rates worldwide, raising extensive concerns on the mechanisms and therapeutic interventions for this disorder. Herein, we described a novel method of establishing MS model in rodents. Male Institute of Cancer Research (ICR) mice were fed with high-fat-high-fructose (HFHF) diet or normal chow (NC) respectively for 12 weeks. Metabolic phenotypes were...
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