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Vitamin B 12 modulates the transcriptome of the skin microbiota in acne pathogenesis

24 Jun 2015

Abstract excerpt

Various diseases have been linked to the human microbiota, but the underlying molecular mechanisms of the microbiota in disease pathogenesis are often poorly understood. Using acne as a disease model, we aimed to understand the molecular response of the skin microbiota to host metabolite signaling in disease pathogenesis. Metatranscriptomic analysis revealed that the transcriptional profiles of the skin...

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PMID: 26109103
DOI: 10.1126/scitranslmed.aab2009

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