Article
Differences in antibiotic-induced oxidative stress responses between laboratory and clinical isolates of Streptococcus pneumoniae.
Antimicrobial agents and chemotherapy - 1 Sept 2015
Dridi Bédis, Lupien Andréanne, Bergeron Michel G, Leprohon Philippe, Ouellette Marc
Abstract excerpt
Oxidants were shown to contribute to the lethality of bactericidal antibiotics in different bacterial species, including the laboratory strain Streptococcus pneumoniae R6. Resistance to penicillin among S. pneumoniae R6 mutants was further shown to protect against the induction of oxidants upon exposure to unrelated bactericidal compounds. In the work described here, we expanded on these results by studying the...
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