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Article

The ZNF304-integrin axis protects against anoikis in cancer

17 Jun 2015

Abstract excerpt

Ovarian cancer (OC) is a highly metastatic disease, but no effective strategies to target this process are currently available. Here, an integrative computational analysis of the Cancer Genome Atlas OC data set and experimental validation identifies a zinc finger transcription factor ZNF304 associated with OC metastasis. High tumoral ZNF304 expression is associated with poor overall survival in OC patients....

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PMID: 26081979
DOI: 10.1038/ncomms8351

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