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Article

Inherited chromosomally integrated human herpesvirus 6 as a predisposing risk factor for the development of angina pectoris.

Proceedings of the National Academy of Sciences of the United States of America - 30 Jun 2015

Gravel Annie, Dubuc Isabelle, Morissette Guillaume, Sedlak Ruth H, Jerome Keith R, Flamand Louis

Abstract excerpt

Inherited chromosomally integrated human herpesvirus-6 (iciHHV-6) results in the germ-line transmission of the HHV-6 genome. Every somatic cell of iciHHV-6+ individuals contains the HHV-6 genome integrated in the telomere of chromosomes. Whether having iciHHV-6 predisposes humans to diseases remains undefined. DNA from 19,597 participants between 40 and 69 years of age were analyzed by quantitative PCR (qPCR) for...

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Identifiers

PMID: 26080419
DOI: 10.1073/pnas.1502741112
PMCID: PMC4491735

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