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Article

Single nucleotide polymorphisms of the GJB2 and GJB6 genes are associated with autosomal recessive nonsyndromic hearing loss.

BioMed research international - 1 Jan 2015

Grillo Ana Paula, de Oliveira Flávia Marcorin, de Carvalho Gabriela Queila, Medrano Ruan Felipe Vieira, da Silva-Costa Sueli Matilde, Sartorato Edi Lúcia, de Oliveira Camila Andréa

Abstract excerpt

Single nucleotide polymorphisms (SNPs) are important markers in many studies that link DNA sequence variations to phenotypic changes; such studies are expected to advance the understanding of human physiology and elucidate the molecular basis of diseases. The DFNB1 locus, which contains the GJB2 and GJB6 genes, plays a key role in nonsyndromic hearing loss. Previous studies have identified important mutations in...

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Identifiers

PMID: 26075227
DOI: 10.1155/2015/318727
PMCID: PMC4449875

Genes

GJB2
GJB6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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