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Article

GJB2 and GJB6 mutations are an infrequent cause of autosomal-recessive nonsyndromic hearing loss in residents of Mexico.

International journal of pediatric otorhinolaryngology - 1 Dec 2014

Hernández-Juárez Aideé Alejandra, Lugo-Trampe José de Jesús, Campos-Acevedo Luis Daniel, Lugo-Trampe Angel, Treviño-González José Luis, de-la-Cruz-Ávila Israel, Martínez-de-Villarreal Laura Elia

Abstract excerpt

OBJECTIVES: Mutations in the DFNB1 locus are the most common cause of autosomal-recessive nonsyndromic hearing loss (ARNSHL) worldwide. The aim of this study was to identify the most frequent mutations in patients with ARNSHL who reside in Northeastern Mexico. METHODS: We determined the nucleotide sequence the coding region of GJB2 of 78 patients with ARNSHL. Polymerase chain reaction assays were used to detect...

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Source

Identifiers

PMID: 25288386
DOI: 10.1016/j.ijporl.2014.09.016

Genes

GJB2
GJB6

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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