Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dysferlin deficiency confers increased susceptibility to coxsackievirus-induced cardiomyopathy.

Cellular microbiology - 1 Oct 2015

Wang Chen, Wong Jerry, Fung Gabriel, Shi Junyan, Deng Haoyu, Zhang Jingchun, Bernatchez Pascal, Luo Honglin

Abstract excerpt

Coxsackievirus infection can lead to viral myocarditis and its sequela, dilated cardiomyopathy, which represent major causes of cardiovascular mortality worldwide in children. Yet, the host genetic susceptible factors and the underlying mechanisms by which viral infection damages cardiac function remain to be fully resolved. Dysferlin is a transmembrane protein highly expressed in skeletal and cardiac muscles. In...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Coxsackievirus Infections
Share to Dysferlin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Membrane Proteins

Share to Myocarditis

Source

Identifiers

PMID: 26073173
DOI: 10.1111/cmi.12473

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dysferlin deficiency confers increased susceptibility to coxsackievirus-induced cardiomyopathy.PMID 26073173Read ↗

Dysferlinopathies.Semantic proximity Read ↗

Dysferlin and Animal Models for DysferlinopathySemantic proximity Read ↗

Dysferlinopathies.Semantic proximity Read ↗

Disruption of muscle membrane and phenotype divergence in two novel mouse models of dysferlin deficiency.Semantic proximity Read ↗

A Naturally Occurring Human Minidysferlin Protein Repairs Sarcolemmal Lesions in a Mouse Model of DysferlinopathySemantic proximity Read ↗

Dysferlin-mediated membrane repair protects the heart from stress-induced left ventricular injurySemantic proximity Read ↗

Muscular dystrophy in dysferlin-deficient mouse models.Semantic proximity Read ↗

Dysfunction of dysferlin-deficient hearts.Semantic proximity Read ↗

The Dysferlinopathies Conundrum: Clinical Spectra, Disease Mechanism and Genetic Approaches for Treatments.Semantic proximity Read ↗

Generation of a novel Dysferlin microdeletion knock-in mouse model mimicking muscular dystrophy-like pathology.Semantic proximity Read ↗

Limb Girdle Muscular Dystrophy Type 2B (LGMD2B): Diagnosis and Therapeutic Possibilities.Semantic proximity Read ↗

Portrait of Dysferlinopathy: Diagnosis and Development of TherapySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.