Article
Neonatal environment exerts a sustained influence on the development of the intestinal microbiota and metabolic phenotype.
The ISME journal - 1 Jan 2016
Merrifield Claire A, Lewis Marie C, Berger Bernard, Cloarec Olivier, Heinzmann Silke S, Charton Florence, Krause Lutz, Levin Nadine S, Duncker Swantje, Mercenier Annick, Holmes Elaine, Bailey Mick, Nicholson Jeremy K
Abstract excerpt
The postnatal environment, including factors such as weaning and acquisition of the gut microbiota, has been causally linked to the development of later immunological diseases such as allergy and autoimmunity, and has also been associated with a predisposition to metabolic disorders. We show that the very early-life environment influences the development of both the gut microbiota and host metabolic phenotype in...
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