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Article

Using genome-wide measures of coancestry to maintain diversity and fitness in endangered and domestic pig populations.

Genome research - 1 Jul 2015

Bosse Mirte, Megens Hendrik-Jan, Madsen Ole, Crooijmans Richard P M A, Ryder Oliver A, Austerlitz Frédéric, Groenen Martien A M, de Cara M Angeles R

Abstract excerpt

Conservation and breeding programs aim at maintaining the most diversity, thereby avoiding deleterious effects of inbreeding while maintaining enough variation from which traits of interest can be selected. Theoretically, the most diversity is maintained using optimal contributions based on many markers to calculate coancestries, but this can decrease fitness by maintaining linked deleterious variants. The...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26063737
DOI: 10.1101/gr.187039.114
PMCID: PMC4484394

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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