Macrophage autophagy protects against liver fibrosis in mice.

Abstract excerpt

Autophagy is a lysosomal degradation pathway of cellular components that displays antiinflammatory properties in macrophages. Macrophages are critically involved in chronic liver injury by releasing mediators that promote hepatocyte apoptosis, contribute to inflammatory cell recruitment and activation of hepatic fibrogenic cells. Here, we investigated whether macrophage autophagy may protect against chronic liver...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Autophagy-Related Protein 5
• Share to Carbon Tetrachloride