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Article

DISMIRA: Prioritization of disease candidates in miRNA-disease associations based on maximum weighted matching inference model and motif-based analysis.

BMC genomics - 1 Jan 2015

Nalluri Joseph J, Kamapantula Bhanu K, Barh Debmalya, Jain Neha, Bhattacharya Antaripa, Almeida Sintia Silva de, Ramos Rommel Thiago Juca, Silva Artur, Azevedo Vasco, Ghosh Preetam

Abstract excerpt

BACKGROUND: MicroRNAs (miRNAs) have increasingly been found to regulate diseases at a significant level. The interaction of miRNA and diseases is a complex web of multilevel interactions, given the fact that a miRNA regulates upto 50 or more diseases and miRNAs/diseases work in clusters. The clear patterns of miRNA regulations in a disease are still elusive. METHODS: In this work, we approach the miRNA-disease...

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PMID: 26040329
DOI: 10.1186/1471-2164-16-S5-S12
PMCID: PMC4461020

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