Article
TLR2, TLR4 and CD86 gene polymorphisms in recurrent aphthous stomatitis.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology - 1 Nov 2015
Karasneh Jumana, Bani-Hani Maisoun, Alkhateeb Asem, Hassan Ahmad, Alzoubi Firas, Thornhill Martin
Abstract excerpt
BACKGROUND: Recurrent aphthous stomatitis (RAS) is an inflammatory disease induced by genetic and environmental factors. Toll-like receptor (TLR) and CD86 are essential components for innate immunity and cellular immune response. We aimed to determine whether inheritance of specific TLR2, TLR4and CD86 gene polymorphisms are associated with RAS. METHODS: Ninety-six patients with RAS and 153 controls were studied....
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