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Article

Potent Immunosuppressive Activities of Cytomegalovirus- Encoded Interleukin-10

1 Feb 2002

Abstract excerpt

Cytomegalovirus (CMV) has highly evolved mechanisms for avoiding detection by the host immune system. Recently, in the genomes of human and primate CMV, a novel gene comprising segments of noncontiguous open reading frames was identified and found to have limited predicted homology to endogenous cellular interleukin-10 (IL-10). Here we investigate the biological activities of the CMV IL-10-like gene product and...

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PMID: 11773404
DOI: 10.1128/jvi.76.3.1285-1292.2002

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