Article
A KCNJ10 mutation previously identified in the Russell group of terriers also occurs in Smooth-Haired Fox Terriers with hereditary ataxia and in related breeds.
Acta veterinaria Scandinavica - 23 May 2015
Rohdin Cecilia, Gilliam Douglas, O'Leary Caroline A, O'Brien Dennis P, Coates Joan R, Johnson Gary S, Jäderlund Karin Hultin
Abstract excerpt
BACKGROUND: Hereditary ataxias with similar phenotypes were reported in the Smooth-Haired Fox Terrier, the Jack Russell Terrier and the Parson Russell Terrier. However, segregation analyses showed differing inheritance modes in these breeds. Recently, molecular genetic studies on the Russell group of terriers found independent mutations in KCNJ10 and CAPN1, each associated with a specific clinical subtype of...
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