Article
Genes Encoding Vascular Endothelial Growth Factor A (VEGF-A) and VEGF Receptor 2 (VEGFR-2) and Risk for Bronchopulmonary Dysplasia.
Neonatology - 1 Jan 2015
Mahlman Mari, Huusko Johanna M, Karjalainen Minna K, Kaukola Tuula, Marttila Riitta, Ojaniemi Marja, Haataja Ritva, Lavoie Pascal M, Rämet Mika, Hallman Mikko
Abstract excerpt
BACKGROUND: Bronchopulmonary dysplasia (BPD) is one of the main consequences of prematurity, with notably high heritability. Vascular endothelial growth factor A (VEGF-A) and its main receptor, vascular endothelial growth factor receptor 2 (VEGFR-2), have been implicated in the pathogenesis of BPD. OBJECTIVE: To study whether common polymorphisms of the genes encoding VEGF-A and VEGFR-2 are associated with BPD....
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