Article
A genome-wide association study (GWAS) for bronchopulmonary dysplasia.
Pediatrics - 1 Aug 2013
Wang Hui, St Julien Krystal R, Stevenson David K, Hoffmann Thomas J, Witte John S, Lazzeroni Laura C, Krasnow Mark A, Quaintance Cecele C, Oehlert John W, Jelliffe-Pawlowski Laura L, Gould Jeffrey B, Shaw Gary M, O'Brodovich Hugh M
Abstract excerpt
OBJECTIVE: Twin studies suggest that heritability of moderate-severe bronchopulmonary dysplasia (BPD) is 53% to 79%, we conducted a genome-wide association study (GWAS) to identify genetic variants associated with the risk for BPD. METHODS: The discovery GWAS was completed on 1726 very low birth weight infants (gestational age = 25(0)-29(6/7) weeks) who had a minimum of 3 days of intermittent positive pressure...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.