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Article

X-linked TEX11 mutations, meiotic arrest, and azoospermia in infertile men.

The New England journal of medicine - 28 May 2015

Yatsenko Alexander N, Georgiadis Andrew P, Röpke Albrecht, Berman Andrea J, Jaffe Thomas, Olszewska Marta, Westernströer Birgit, Sanfilippo Joseph, Kurpisz Maciej, Rajkovic Aleksandar, Yatsenko Svetlana A, Kliesch Sabine, Schlatt Stefan, Tüttelmann Frank

Abstract excerpt

BACKGROUND: The genetic basis of nonobstructive azoospermia is unknown in the majority of infertile men. METHODS: We performed array comparative genomic hybridization testing in blood samples obtained from 15 patients with azoospermia, and we performed mutation screening by means of direct Sanger sequencing of the testis-expressed 11 gene (TEX11) open reading frame in blood and semen samples obtained from 289...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25970010
DOI: 10.1056/NEJMoa1406192
PMCID: PMC4470617

Genes

TEX11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

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Research trail→

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X-linked TEX11 mutations, meiotic arrest, and azoospermia in infertile men.PMID 25970010Read ↗

A new TEX11 mutation causes azoospermia and testicular meiotic arrest.Semantic proximity Read ↗

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Novel biallelic MCMDC2 variants were associated with meiotic arrest and nonobstructive azoospermia.Semantic proximity Read ↗

Words of Wisdom. Re: X-Linked TEX11 Mutations, Meiotic Arrest, and Azoospermia in Infertile Men.Semantic proximity Read ↗

TEX11 is mutated in infertile men with azoospermia and regulates genome-wide recombination rates in mouse.Semantic proximity Read ↗

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Scrutinizing the human TEX genes in the context of human male infertilitySemantic proximity Read ↗

A Novel Compound Heterozygous Mutation in TEX14 Causes Human Non-Obstructive Azoospermia by Disrupting the Assembly of Intercellular Bridges.Semantic proximity Read ↗

Genetic insights into non-obstructive azoospermia: Implications for diagnosis and TESE outcomesSemantic proximity Read ↗

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