Article
Role of NF-κB activation and VEGF gene polymorphisms in VEGF up regulation in non-proliferative and proliferative diabetic retinopathy.
Molecular and cellular biochemistry - 1 Jul 2015
Choudhuri Subhadip, Chowdhury Imran H, Das Shibali, Dutta Deep, Saha Avijit, Sarkar Rajarshi, Mandal Lakshmi K, Mukherjee Satinath, Bhattacharya Basudev
Abstract excerpt
The present study was aimed to investigate the relation between nuclear factor kappa beta (NFκB) activation and downstream up-regulation of vascular endothelial growth factor (VEGF) in diabetic retinopathy (DR). Moreover the study was intended to evaluate the role of VEGF gene single nucleotide polymorphisms (SNPs) in DR occurrence and to investigate the functional relevance of VEGF gene SNPs in terms of VEGF...
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